Endocrine Abstracts

Glucose metabolism alterations are frequently observed in acromegalic patients. Somatostatin analogues (SSTA) are the most widely used drugs to treat acromegaly, since they inhibit GH and IGF-1 levels, reduce pituitary mass, but can affect glucose metabolism. Aim of our study was to evaluate glucose metabolism alterations in acromegalic patients cured after surgery and in patients with active disease during treatment with SSTA. We studied 10 patients (group A, 5F, 55.66±1...

Nonfunctioning adenomas (NFA) are 30% of all pituitary adenomas. Transphenoidal surgery is the first line therapy, but recurrences are frequent (12% al 69%). NFA treatment and follow-up are controversial. Aim of our study was to evaluate the recurrence prevalence and the factors associated with tumor aggressiveness in patients with NFA. We studied 30 patients that underwent surgery: 14 patients (group A, 7F, 3.92±12.48 years) with and 16 patients (group B, 6F, 56.5±1...